QR-Code

TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated

<p>Abstract</p> <p>Background</p> <p>Degraded extracellular matrix can stimulate the innate immune system via the Toll-Like Receptor-4 (TLR4). In the pancreas, syndecan-anchored heparan sulphate (HS) on the ductal epithelium can be cleaved off its protein cores by the proteases (trypsin and elastase...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Akbarshahi Hamid, Axelsson Jakob BF, Said Katarzyna, Malmström Anders, Fischer Hans, Andersson Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2011-12-01
Schriftenreihe:Journal of Translational Medicine
Schlagworte:
Heparan sulphate
pancreas
inflammation
Toll Like Receptor-4
Interferon Regulatory Factor 3
Online-Zugang:http://www.translational-medicine.com/content/9/1/219
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge