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Curcumin and Andrographis Exhibit Anti-Tumor Effects in Colorectal Cancer via Activation of Ferroptosis and Dual Suppression of Glutathione Peroxidase-4 and Ferroptosis Suppressor Protein-1

Colorectal cancer (CRC) is the leading cause of cancer-related deaths worldwide. The limitations of current chemotherapeutic drugs in CRC include their toxicity, side effects, and exorbitant costs. To assess these unmet needs in CRC treatment, several naturally occurring compounds, including curcumi...

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Principais autores: Katsuki Miyazaki, Caiming Xu, Mitsuo Shimada, Ajay Goel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Pharmaceuticals
Fag:
curcumin
andrographis
glutathione peroxidase 4
ferroptosis suppressor protein 1
natural products
colorectal cancer
Online adgang:https://www.mdpi.com/1424-8247/16/3/383
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