Low oxygen preconditioning of umbilical cord MSCs: from biological to mechanistic innovation

Abstract Background Umbilical cord-derived mesenchymal stem cells (UC-MSCs) represent a highly promising resource for regenerative medicine due to their potent immunomodulatory and proliferative capabilities, low immunogenicity, and ease of non-invasive collection. However, the low-oxygen (hypoxic)...

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Autors principals:	Maryam Hazeri, Wan Safwani Wan Kamarul Zaman, Morvarid Akhavan Rezaei, Pezhman Hafez, Tan Xin Yee, Rashidi Dzul Keflee, Hanita Mohd Hussin, Muhammad Al Bunyamin Abdul Rahman
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Journal of Translational Medicine
Matèries:	Umbilical cord mesenchymal stem cells (UC-MSCs) Hypoxia preconditioning Immunomodulation Hypoxia-inducible factors (HIFs) Stem cell therapy Cell survival and proliferation
Accés en línia:	https://doi.org/10.1186/s12967-026-08026-z
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