Primary Human Renal Proximal Tubular Epithelial Cells (pHRPTEpiCs): Shiga Toxin (Stx) Glycosphingolipid Receptors, Stx Susceptibility, and Interaction with Membrane Microdomains

Tubular epithelial cells of the human kidney are considered as targets of Shiga toxins (Stxs) in the Stx-mediated pathogenesis of hemolytic–uremic syndrome (HUS) caused by Stx-releasing enterohemorrhagic <i>Escherichia coli</i> (EHEC). Analysis of Stx-binding glycosphingolipids (GSLs) of primary hum...

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主要な著者:	Johanna Detzner, Anna-Lena Klein, Gottfried Pohlentz, Elisabeth Krojnewski, Hans-Ulrich Humpf, Alexander Mellmann, Helge Karch, Johannes Müthing
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2021-07-01
シリーズ:	Toxins
主題:	detergent-resistant membranes glycolipids kidney epithelial cells lipid rafts Stx1a Stx2a
オンライン･アクセス:	https://www.mdpi.com/2072-6651/13/8/529
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