Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression

Abstract The clinical efficacy of immune checkpoint blockade (ICB) therapy is significantly compromised in the metabolically disordered tumor microenvironment (TME), posing a formidable challenge that cannot be ignored in current antitumor strategies. In this study, TME‐responsive nanoparticles (HMP...

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Principais autores:	Mengna Wang, Yuhong Liu, Yanshi Li, Tao Lu, Min Wang, Zhaobo Cheng, Lin Chen, Tongling Wen, Min Pan, Guohua Hu
格式:	Artigo
語言:	Inglês
出版:	Wiley 2025-02-01
叢編:	Advanced Science
主題:	chemodymic therapy immunosuppression indoleamine 2,3‐dioxygenase 1 KYN/TRP metabolism
在線閱讀:	https://doi.org/10.1002/advs.202405845
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