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Rutaecarpine Aggravates Acetaminophen-Induced Acute Liver Injury by Inducing CYP1A2

In this study, we investigated whether rutaecarpine could aggravate acetaminophen-induced acute liver damage in vivo and in vitro. CCK-8 and apoptosis assays were performed to verify the cytotoxicity of acetaminophen to L02 cells with or without rutaecarpine. The expression levels of the target prot...

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Auteurs principaux: Meiqi Wan, Hua Gao, Xiaoyan Liu, Youbo Zhang
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2024-07-01
Collection:Toxics
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Accès en ligne:https://www.mdpi.com/2305-6304/12/7/515
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