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Characterization of the nuclear import mechanism of the CCAAT-regulatory subunit Php4.

Php4 is a nucleo-cytoplasmic shuttling protein that accumulates in the nucleus during iron deficiency. When present in the nucleus, Php4 associates with the CCAAT-binding protein complex and represses genes encoding iron-using proteins. Here, we show that nuclear import of Php4 is independent of the...

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Bibliografiske detaljer
Principais autores: Md Gulam Musawwir Khan, Jean-François Jacques, Jude Beaudoin, Simon Labbé
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4201560?pdf=render
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