Therapeutic strategies for spinal muscular atrophy: SMN and beyond

Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder characterized by loss of motor neurons and muscle atrophy, generally presenting in childhood. SMA is caused by low levels of the survival motor neuron protein (SMN) due to inactivating mutations in the encoding gene SMN1. A second...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Melissa Bowerman, Catherina G. Becker, Rafael J. Yáñez-Muñoz, Ke Ning, Matthew J. A. Wood, Thomas H. Gillingwater, Kevin Talbot, The UK SMA Research Consortium
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	The Company of Biologists 2017-08-01
Цуврал:	Disease Models & Mechanisms
Нөхцлүүд:	Animal models Cellular models Combinatorial therapies Skeletal muscle Spinal muscular atrophy Survival motor neuron
Онлайн хандалт:	http://dmm.biologists.org/content/10/8/943
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!