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Acute and chronic nasal inflammation induces lymphangiogenesis in the olfactory mucosa in mice

Background: Lymphangiogenesis, the formation of new lymphatic vessels, is primarily driven by VEGF-C-mediated activation of VEGFR-3 and plays a critical role in immune regulation and tissue repair. Although lymphangiogenesis has been well documented in various inflamed tissues, its occurrence and sp...

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Principais autores: Suzuho Komaki, Ryuichi Imai, Yuzuki Sugimoto, Rei Settsu, Aki Obara, Atsuyoshi Shimada, Robert Dantzer, Geoffroy Laumet, Fumiaki Imamura, Sanae Hasegawa-Ishii
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-11-01
coleção:Brain, Behavior, & Immunity - Health
Assuntos:
Nasal inflammation
Lymphangiogenesis
Olfactory mucosa
VEGF-C
Lyve-1
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666354625001772
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