MRI Epicenters Differentiate Spatiotemporal Patterns of Neurodegeneration in Parkinson's Disease

Abstract Parkinson's disease (PD) exhibits clinical and neuropathological heterogeneity, potentially driven by distinct spatiotemporal neurodegenerative patterns. This study utilizes a connectivity‐based MRI epicenter model combined with unsupervised clustering to identify unique degenerative epicen...

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Библиографические подробности

Главные авторы:	Xiaojie Duanmu, Zihao Zhu, Jiaqi Wen, Jianmei Qin, Qianshi Zheng, Weijin Yuan, Yingni Jin, Nan Lu, Lu Wang, Cheng Zhou, Tao Guo, Haoting Wu, Chenqing Wu, Ziyi Zhu, Lifang Wang, Jingwen Chen, Jingjing Wu, Bingting Zhu, Yuelin Fang, Yaping Yan, Baorong Zhang, Minming Zhang, Xiaojun Guan, Xiaojun Xu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2025-12-01
Серии:	Advanced Science
Предметы:	connectivity‐based epicenter model deformation‐based morphometry diffusion tensor imaging quantitative susceptibility imaging
Online-ссылка:	https://doi.org/10.1002/advs.202511289
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