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Harnessing PDX and PDX 2.0: the next-generation paradigm for precision oncology and translational breakthroughs

Abstract Cancer research has achieved remarkable breakthroughs over the past decades with the aid of patient-derived xenograft (PDX) models. However, the limitations of conventional PDX models in hindering clinical translation have become increasingly apparent. In 2025, the National Institutes of He...

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Autors principals: Chengli Jian, Hao Fu, Wantao Wu, Nan Zhang, Zaoqu Liu, Zhiwei Xia, Peng Luo, Hao Zhang, Quan Cheng
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-02-01
Col·lecció:Molecular Cancer
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Accés en línia:https://doi.org/10.1186/s12943-026-02594-w
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