Diverse viral proteases activate the NLRP1 inflammasome
The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains of NLRP1B and liberation of the bioactive C-termin...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2021-01-01
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| Series: | eLife |
| Assuntos: | |
| Acceso en liña: | https://elifesciences.org/articles/60609 |
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