PROGNOSTIC IMPACT OF ISOCITRATE DEHYDROGENASE ENZYME ISOFORMS IDH1 & IDH2 MUTATIONS IN ACUTE MYELOID LEUKEMIA
Background: IDH1 & 2 mutations are one of the most common genomic abnormalities which have recently been described in acute myeloid leukemia (AML) patients. Mutant IDH1/2 enzymes have neomorphic activity and catalyze the reduction of ketoglutarate to an oncometabolite, which promotes DNA and his...
I tiakina i:
| Ngā kaituhi matua: | , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Ain Shams University; Faculty of Medicine. Ain Shams Clinical and Scientific Society
2019-07-01
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| Rangatū: | Ain Shams Medical Journal |
| Ngā marau: | |
| Urunga tuihono: | https://asmj.journals.ekb.eg/article_101271_65e95da56de165e8e49c428a359b5330.pdf |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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