Scratching increases epidermal neuronal branching and alters psychophysical testing responses in atopic dermatitis and brachioradial pruritus

BackgroundChronic scratching imposes a major stress on the skin and can lead to itch intensity worsening, and consequently, patients may enter an itch–scratch cycle. This repetitive mechanical stress can result in lichenification, worsening of epidermal barrier function, and enhanced cutaneous infla...

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Autori principali:	Lina Renkhold, Henning Wiegmann, Bettina Pfleiderer, Aysenur Süer, Claudia Zeidler, Manuel P. Pereira, Martin Schmelz, Sonja Ständer, Konstantin Agelopoulos
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-09-01
Serie:	Frontiers in Molecular Neuroscience
Soggetti:	chronic pruritus (CP) chronic scratching lichenification atopic dermatitis (AD) brachioradial pruritus IENF density
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1260345/full
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