Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion
Double strand breaks (DSBs) are preferentially repaired by sister-chromatid recombination (SCR) to maintain genome stability. Here, the authors reveal a role for histone deacetylate (HDAC) complexes favouring the repair of replication related DSBs by facilitating cohesin loading.
Na minha lista:
| Principais autores: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2019-11-01
|
| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-019-13210-5 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|