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Adult Human, but Not Rodent, Spermatogonial Stem Cells Retain States with a Foetal-like Signature

Spermatogenesis involves a complex process of cellular differentiation maintained by spermatogonial stem cells (SSCs). Being critical to male reproduction, it is generally assumed that spermatogenesis starts and ends in equivalent transcriptional states in related species. Based on single-cell gene...

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Principais autores: Stephen J. Bush, Rafail Nikola, Seungmin Han, Shinnosuke Suzuki, Shosei Yoshida, Benjamin D. Simons, Anne Goriely
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-04-01
coleção:Cells
Assuntos:
germline
single-cell RNA-sequencing
cell cycle
quiescence
cross-species comparison
Acesso em linha:https://www.mdpi.com/2073-4409/13/9/742
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