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Screening of Neutrophil Activating Factors from a Metagenome Library of Sponge-Associated Bacteria

Marine sponge-associated bacteria are known as bio-active compound produce. We have constructed metagenome libraries of the bacteria and developed a metagenomic screening approach. Activity-based screening successfully identified novel genes and novel enzymes; however, the efficiency was only in 1 o...

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Principais autores: Yoshiko Okamura, Hirokazu Takahashi, Atsuyuki Shiida, Yuto Hirata, Haruko Takeyama, Katsuhiko Suzuki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-07-01
Serier:Marine Drugs
Fag:
activity-based screening
bioactive compound
metagenome analysis
neutrophil activating peptide
Online adgang:https://www.mdpi.com/1660-3397/19/8/427
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