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Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors

Abstract Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability. Their chemical structure allows the insertion of reporter molecules and surface-binding agents in specific locations, which have b...

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Detalles Bibliográficos
Principais autores: Iman Jeddi, Leonor Saiz
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2017-04-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-017-01348-5
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