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Role of NDE1 in the Development and Evolution of the Gyrified Cortex

An expanded cortex is a hallmark of human neurodevelopment and endows increased cognitive capabilities. Recent work has shown that the cell cycle-related gene NDE1 is essential for proper cortical development. Patients who have mutations in NDE1 exhibit congenital microcephaly as a primary phenotype...

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Bibliografiske detaljer
Principais autores: Jaseph Soto-Perez, Marybeth Baumgartner, Rahul N. Kanadia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-12-01
Serier:Frontiers in Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fnins.2020.617513/full
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