The Highs and Lows of FBXW7: New Insights into Substrate Affinity in Disease and Development
FBXW7 is a critical regulator of cell cycle, cell signaling, and development. A highly conserved F-box protein and component of the SKP1–Cullin–F-box (SCF) complex, FBXW7 functions as a recognition subunit within a Cullin–RING E3 ubiquitin ligase responsible for ubiquitinating substrate proteins and...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI AG
2023-08-01
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| Colección: | Cells |
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| Acceso en línea: | https://www.mdpi.com/2073-4409/12/17/2141 |
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