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Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2

During neuronal differentiation, use of an alternative splice site on the rat telomere repeat-binding factor 2 (TRF2) mRNA generates a short TRF2 protein isoform (TRF2-S) capable of derepressing neuronal genes. However, the RNA-binding proteins (RBPs) controlling this splicing event are unknown. Her...

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Hlavní autoři: Ioannis Grammatikakis, Peisu Zhang, Amaresh C. Panda, Jiyoung Kim, Stuart Maudsley, Kotb Abdelmohsen, Xiaoling Yang, Jennifer L. Martindale, Omar Motiño, Emmette R. Hutchison, Mark P. Mattson, Myriam Gorospe
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016-05-01
Edice:Cell Reports
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211124716303692
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