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TCRMatch: Predicting T-Cell Receptor Specificity Based on Sequence Similarity to Previously Characterized Receptors

The adaptive immune system in vertebrates has evolved to recognize non-self antigens, such as proteins expressed by infectious agents and mutated cancer cells. T cells play an important role in antigen recognition by expressing a diverse repertoire of antigen-specific receptors, which bind epitopes...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: William D. Chronister, Austin Crinklaw, Swapnil Mahajan, Randi Vita, Zeynep Koşaloğlu-Yalçın, Zhen Yan, Jason A. Greenbaum, Leon E. Jessen, Morten Nielsen, Scott Christley, Lindsay G. Cowell, Alessandro Sette, Bjoern Peters
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-03-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
T cell
epitope
sequence similarity
immune repertoire analysis
IEDB
epitope prediction tool
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.640725/full
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