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Caffeine May Delay the Radiation-Induced Nucleoshuttling of the ATM Kinase and Reduce the Recognition of the DNA Double-Strand Breaks in Human Cells

Since 2014, a model of the individual response to ionizing radiation (IR), based on the radiation-induced nucleoshuttling of the ATM protein kinase (RIANS), has been developed by our lab: after irradiation, ATM dimers monomerize in cytoplasm and diffuse into the nucleus to trigger both recognition a...

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Autors principals: Léonie Moliard, Juliette Restier-Verlet, Joëlle Al-Choboq, Adeline Granzotto, Laurent Charlet, Jacques Balosso, Michel Bourguignon, Laurent Pujo-Menjouet, Nicolas Foray
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-12-01
Col·lecció:Biomolecules
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Accés en línia:https://www.mdpi.com/2218-273X/16/1/41
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