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Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Summary: Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1). In this study we examine if bacteria residing on the skin are influenced by the loss of LEKTI-1 and if interaction between this human gene...

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Príomhchruthaitheoirí: Michael R. Williams, Laura Cau, Yichen Wang, Drishti Kaul, James A. Sanford, Livia S. Zaramela, Shadi Khalil, Anna M. Butcher, Karsten Zengler, Alexander R. Horswill, Christopher L. Dupont, Alain Hovnanian, Richard L. Gallo
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Elsevier 2020-03-01
Sraith:Cell Reports
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2211124720301753
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