Outcomes of autologous bone marrow mononuclear cell administration combined with educational intervention in the treatment of autism spectrum disorder: a randomized, open-label, controlled phase II clinical trial

Abstract Background This study evaluated the effectiveness of intrathecal autologous bone marrow mononuclear cell (BMMNC) therapy combined with education compared with education alone for the treatment of autism spectrum disorder (ASD). Methods Fifty-four children with ASD, aged three to seven years...

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Principais autores:	Liem Thanh Nguyen, Phuong Mai Nguyen, Hoang-Phuong Nguyen, Hau Thi Bui, Lan Thi Mai Dao, Minh Van Pham, Chi Khanh Hoang, Phuong Thi Nguyen, Thao Thi Phuong Nguyen, Anh Thi Phuong Nguyen, Van Thi Hoang, Hoa Thi Phuong Bui, Ngan Kim Vuong, Doan Van Ngo
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-05-01
Series:	Stem Cell Research & Therapy
Assuntos:	Autism spectrum disorder Bone marrow mononuclear cells Intrathecal infusion Randomized phase II clinical trial Cell therapy
Acceso en liña:	https://doi.org/10.1186/s13287-025-04404-4
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