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A comparison of strategies for generating artificial replicates in RNA-seq experiments

Abstract Due to the overall high costs, technical replicates are usually omitted in RNA-seq experiments, but several methods exist to generate them artificially. Bootstrapping reads from FASTQ-files has recently been used in the context of other NGS analyses and can be used to generate artificial te...

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Auteurs principaux: Babak Saremi, Frederic Gusmag, Ottmar Distl, Frank Schaarschmidt, Julia Metzger, Stefanie Becker, Klaus Jung
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2022-05-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-022-11302-9
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