Advancing PEGylated Drug Evaluation: A Novel Approach to Pegfilgrastim Pharmacokinetic Assessment
ABSTRACT Addition of polyethylene glycol (PEG), or PEGylation, is a modification that extends the half‐life of drug products, thereby reducing the frequency of dosing. However, PEGylation can pose challenges for biosimilar drug development, as replicating the reference product's PEG characteristics...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2026-07-01
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| coleção: | Clinical and Translational Science |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1111/cts.70588 |
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