The relationship between CSF/serum immunoglobulin and albumin ratio across laboratories: a retrospective, multi-center study

Abstract Background The relationship between cerebrospinal fluid (CSF)/serum immunoglobulin (Ig) ratios (QIg) and CSF/serum albumin ratio (Qalb) is a commonly used biomarker in routine CSF diagnostics. It is used to quantitatively determine the presence of an intrathecal Ig synthesis, which is impor...

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Autors principals:	Harald Hegen, Ulf Andreasson, Juan J. Archelos-Garcia, Gerhard Bachmaier, Kaj Blennow, Gabriel Bsteh, Isabelle Hubeek, Michael Khalil, Jens Kuhle, H. Bea Kuiperij, Jan Lycke, Igal Rosenstein, Charlotte E. Teunissen, Marcel M. Verbeek, Michel Willemsen, Henrik Zetterberg, Janette Walde, Florian Deisenhammer
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-12-01
Col·lecció:	Fluids and Barriers of the CNS
Matèries:	Cerebrospinal fluid Immunoglobulin Albumin Intrathecal synthesis Formula Intrathecal fraction
Accés en línia:	https://doi.org/10.1186/s12987-025-00747-5
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