Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced SteatosisSummary

Background & Aims: Cholesterol 25-hydroxylase (Ch25h), converting cholesterol to 25-hydroxycholesterol (25-HC), is critical in modulating cellular lipid metabolism and anti-inflammatory and antiviral activities. However, its role in nonalcoholic fatty liver disease remains unclear. Methods: Ch25...

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Hlavní autoři:	Zeyu Dong, Fangzhou He, Xiaosong Yan, Yuanming Xing, Yuyang Lei, Jie Gao, Ming He, Dongmin Li, Liang Bai, Zuyi Yuan, John Y-J. Shyy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-01-01
Edice:	Cellular and Molecular Gastroenterology and Hepatology
Témata:	25-HC Bile Acid Metabolism Ch25h CYP7A1 Hepatic Steatosis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2352345X2100271X
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