Development of a RP-HPLC method for evaluation of in vitro permeability of voriconazole in the presence of enhancers through rat skin

Abstract An isocratic RP-HPLC–UV method for the analysis of voriconazole in skin diffusate samples has been developed and validated. Experimental design was employed to optimize the method. The method was validated as per ICH guidelines. Linearity was observed over the concentration range of 2–100 μ...

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主要な著者:	M. Vamsi Krishna, Rajendra N. Dash, P. Venugopal, B. Jalachandra Reddy, P. Sandeep, G. Madhavi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer 2013-07-01
シリーズ:	Journal of Saudi Chemical Society
主題:	Voriconazole RP-HPLC Permeation enhancers Skin diffusate samples
オンライン･アクセス:	https://doi.org/10.1016/j.jscs.2013.07.003
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