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hnRNPU is required for spermatogonial stem cell pool establishment in mice

Summary: The continuous regeneration of spermatogonial stem cells (SSCs) underpins spermatogenesis and lifelong male fertility, but the developmental origins of the SSC pool remain unclear. Here, we document that hnRNPU is essential for establishing the SSC pool. In male mice, conditional loss of hn...

Deskribapen osoa

Gorde:
Egile Nagusiak: Yujiao Wen, Shumin Zhou, Yiqian Gui, Zeqing Li, Lisha Yin, Wenchao Xu, Shenglei Feng, Xixiang Ma, Shiming Gan, Mengneng Xiong, Juan Dong, Keren Cheng, Xiaoli Wang, Shuiqiao Yuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-04-01
Saila:Cell Reports
Gaiak:
CP: Developmental biology
CP: Stem cell research
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2211124724004418
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