Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

Abstract Background The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic changes that can eventually affect epithelial homeostasis, predisposing the patient to cancer development. One of the many molecular changes desc...

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主要な著者:	Camile B. Lopes, Leandro L. Magalhães, Carolina R. Teófilo, Ana Paula N. N. Alves, Raquel C. Montenegro, Massimo Negrini, Ândrea Ribeiro-dos-Santos
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2018-07-01
シリーズ:	BMC Cancer
主題:	Oral cancer Field cancerization miRNAs Biomarkers
オンライン･アクセス:	http://link.springer.com/article/10.1186/s12885-018-4631-z
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