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Elevated expression of the serine-arginine protein kinase 1 gene in ovarian cancer and its role in Cisplatin cytotoxicity in vitro.

Alternatively spliced variants of several oncogenes and tumor suppressors have been shown to be important for their tumorigenicity. In the present study we have tested whether serine-arginine protein kinase 1 (SRPK1), a major regulator of splicing factors, is involved in ovarian cancer progression a...

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Autors principals: Kunle Odunsi, Paulette Mhawech-Fauceglia, Christopher Andrews, Amy Beck, Olajumoke Amuwo, Shashikant Lele, Jennifer D Black, Ruea-Yea Huang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3517604?pdf=render
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