β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. A 20% of familial ALS cases are associated with mutations in the gene coding for superoxide dismutase 1 (SOD1). The accumulation of abnormal aggregates of different proteins is a common feature in...

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Үндсэн зохиолчид:	Cristina Pinto, Danilo B. Medinas, Francisco Fuentes-Villalobos, Jaime Maripillán, Ariel F. Castro, Agustín D. Martínez, Nelson Osses, Claudio Hetz, Juan P. Henríquez
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2019-10-01
Цуврал:	Neurobiology of Disease
Нөхцлүүд:	β-Catenin Accumulation ALS Motor neuron GSK3β inhibition Differentiation
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0969996119301524
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!