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Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle

Hepatitis C virus (HCV) is an oncogenic virus that causes chronic liver disease in more than 80% of patients. During the last decade, efficient direct-acting antivirals were introduced into clinical practice. However, clearance of the virus does not reduce the risk of end-stage liver diseases to the...

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Principais autores: Natalia F. Zakirova, Olga A. Khomich, Olga A. Smirnova, Jennifer Molle, Sarah Duponchel, Dmitry V. Yanvarev, Vladimir T. Valuev-Elliston, Lea Monnier, Boyan Grigorov, Olga N. Ivanova, Inna L. Karpenko, Mikhail V. Golikov, Cedric Bovet, Barbara Rindlisbacher, Alex R. Khomutov, Sergey N. Kochetkov, Birke Bartosch, Alexander V. Ivanov
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Cells
Fag:
hepatitis C virus
polyamines
urea cycle
proline metabolism
antiviral agents
Online adgang:https://www.mdpi.com/2073-4409/13/12/1036
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