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Determinants of transthyretin levels and their association with adverse clinical outcomes among UK Biobank participants

Abstract Transthyretin is a transport protein whose misfolding has been implicated in the development of cardiac amyloidosis. Here, we examine the clinical correlates of transthyretin levels, the differences in transthyretin levels according to the pathogenic V142I TTR variant carrier status, and th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Naman S. Shetty, Mokshad Gaonkar, Nirav Patel, Akhil Pampana, Nehal Vekariya, Peng Li, Garima Arora, Pankaj Arora
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-07-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-024-50231-1
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