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Sting and p53 DNA repair pathways are compromised in Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is the most common cause of dementia. A common finding in AD is DNA damage. Double-strand DNA breaks (DSBs) are particularly hazardous to neurons because their post-mitotic state forces neurons to rely on error-prone and potentially mutagenic mechanisms to repair DN...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Thomas J. Nelson, Yunhui Xu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2023-05-01
Rangatū:Scientific Reports
Urunga tuihono:https://doi.org/10.1038/s41598-023-35533-6
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