Endothelial cells under disturbed flow release extracellular vesicles to promote inflammatory polarization of macrophages and accelerate atherosclerosis

Abstract Background Extracellular vesicles (EVs) derived from endothelial cells (ECs) are increasingly recognized for their role in the initiation and progression of atherosclerosis. ECs experience varying degrees and types of blood flow depending on their specific arterial locations. In regions of...

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Detalhes bibliográficos

Principais autores:	Zhe Hou, Li Deng, Fei Fang, Ting Zhao, Yaojia Zhang, Gang Li, Michael Z. Miao, Yongcang Zhang, Hongchi Yu, Xiaoheng Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-01-01
Colecção:	BMC Biology
Assuntos:	Disturbed flow Endothelial cells Extracellular vesicle Macrophages Atherosclerosis
Acesso em linha:	https://doi.org/10.1186/s12915-025-02125-x
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