Modulation of Antigenic Location Converts Chronic into Acute Infection by Forcing CD8+ T Cell Recognition
Pathogens that reside in the phagosomes of infected cells persist despite the presence of potent T cell responses. We addressed the mechanism of immune evasion by using a mouse model of Salmonella typhimurium (ST). Recombinants of ST were generated that translocated antigen to the cytosol or phagoso...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2012-12-01
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| Serier: | Cell Reports |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2211124712003798 |
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