Age-Dependent Loss of Sirtuin1 (Sirt1) Correlates with Reduced Autophagy in Type 2 Diabetic Patients (T2DM)

<b>Aims and Background:</b> Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder frequently associated with increased inflammation and dysregulated innate immune responses. Thus, patients with T2DM are predisposed to bacterial infections. However, the underlying mechanism is poorly unders...

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Detalhes bibliográficos

Principais autores:	Julia Fischer, Nina Judith Hos, Sophie Tritschler, Joel Schmitz-Peters, Raja Ganesan, Chiara Calabrese, Petra Schiller, Hannah Brunnert, Angela Nowag, Sandra Winter, Ruth Hanßen, Katja Römer, Nazifa Qurishi, Isabelle Suarèz, Norma Jung, Clara Lehmann, Georg Plum, Michael Faust, Pia Hartmann, Nirmal Robinson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-05-01
coleção:	Diabetology
Assuntos:	type 2 diabetes mellitus PBMC Sirtuin1 autophagy
Acesso em linha:	https://www.mdpi.com/2673-4540/6/6/45
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