Rational Design and Lead Optimisation of Potent Antimalarial Quinazolinediones and Their Cytotoxicity against MCF-7

Quinazolinedione is one of the most outstanding heterocycles in medicinal chemistry thanks to its wide ranges of biological activities including antimalarial, anticancer, and anti-inflammatory. TCMDC-125133 containing a quinazolinedione pharmacophore displays promising antimalarial activity and low...

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Principais autores:	Sitthivut Charoensutthivarakul, Duangporn Lohawittayanan, Phongthon Kanjanasirirat, Kedchin Jearawuttanakul, Sawinee Seemakhan, Napason Chabang, Patrick Schlaeppi, Varisa Tantivess, Tanapol Limboonreung, Matthew Phanchana
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2023-03-01
סדרה:	Molecules
נושאים:	quinazolinedione derivatives antimalarial activity antiproliferative activity
גישה מקוונת:	https://www.mdpi.com/1420-3049/28/7/2999
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!