Tenofovir Hot-Melt Granulation using Gelucire^® to Develop Sustained-Release Vaginal Systems for Weekly Protection against Sexual Transmission of HIV

Hot-melt granulation is a technique used to obtain granules by dispersing a drug in polymers at a high temperature. Tenofovir, an antiretroviral drug with proven activity as a vaginal microbicide, was dispersed in melted Gelucire^® (or a mixture of different Gelucire^®)...

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Päätekijät:	Fernando Notario-Pérez, Raúl Cazorla-Luna, Araceli Martín-Illana, Roberto Ruiz-Caro, Juan Peña, María-Dolores Veiga
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2019-03-01
Sarja:	Pharmaceutics
Aiheet:	controlled release ex vivo bioadhesion Gelucire<sup>®</sup> Human Immunodeficiency Virus mucoadhesive vaginal compacts Tenofovir
Linkit:	https://www.mdpi.com/1999-4923/11/3/137
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