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Ameliorative effect of pomegranate peel extract nanoparticles and ovarian stem cells-derived exosomes on cyclophosphamide-induced premature ovarian insufficiency

Abstract Background Premature ovarian insufficiency (POI) is a fertility disorder impacting women under 40, characterized by an early deterioration of ovarian function, and is one of the major side effects caused by chemotherapy. Cyclophosphamide is a powerful chemotherapeutic agent used in various...

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Principais autores: Hamdy Y. Ismail, Mariam F. Farid, Nora A. Shaker, Tahsin Shoala, Adel F. Tohamy, Marwa A. Ibrahim, Hamdy Rizk, Y. R. Wally
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:Biological Research
Fag:
Fertility
Cyclophosphamide
Nanotechnology
Exosome
Punica granatum
Online adgang:https://doi.org/10.1186/s40659-025-00664-9
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