Multimodal profiling of immune responses reveals innate-adaptive immune imbalance in human bornavirus encephalitis

Abstract Human bornavirus encephalitis (BVE) is a rare, emerging and fatal zoonotic disease mainly caused by the Borna disease virus 1 (BoDV-1), a non-cytolytic RNA virus. Despite increasing recognition, the immunopathogenesis of human BoDV-1 infection remains insufficiently characterised. Complete...

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Principais autores:	Nicola Jungbäck, Przemyslaw Grochowski, Daniel Hieber, Moritz Dinser, Zuzanna Mielewczyk, Thomas Pfefferkorn, Birgit Muntau, Thomas Richter, Georg Rieder, Antonios Bayas, Klaus Hirschbühl, Bruno Märkl, Patrick Adam, Dennis Tappe, Friederike Liesche-Starnecker
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-05-01
Series:	Acta Neuropathologica Communications
Assuntos:	BoDV-1 Encephalitis Neurotropic virus Immunopathogenesis Transcriptome
Acceso en liña:	https://doi.org/10.1186/s40478-026-02319-6
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