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The Time-Dependent Effects of Temozolomide on Autophagy Gene Expression in Glioblastoma Cells

<b>Background</b>: Temozolomide (TMZ) resistance represents a major therapeutic challenge in glioblastoma treatment, where autophagy has emerged as a key adaptive survival mechanism. Although numerous studies have implicated autophagy in TMZ resistance, most have assessed this process at a single po...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: İlker Kiraz, Veli Kaan Aydın, Özgür Kurt, Mehmet Erdal Coşkun, Gergana Lengerova, Martina Bozhkova, Steliyan Petrov, Aylin Köseler
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-03-01
Schriftenreihe:Biomedicines
Schlagworte:
glioblastoma
temozolomide
autophagy
time-dependent gene expression
chemoresistance
Online-Zugang:https://www.mdpi.com/2227-9059/14/3/656
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