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Moderate iron deficiency and high dietary iron intake differentially alter hepatic lipid metabolism and adipose tissue lipid handling in mice

BackgroundIron (Fe) is an essential micronutrient, yet both its deficiency and overload have been associated with disruptions in lipid metabolism. This study investigated the effects of moderate iron deficiency and high dietary iron on lipid metabolic pathways in mice.MethodsFive-week male C57BL/6J...

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Principais autores: Shangjie Wu, Pengwei Li, Qian Liu, Keying Zhang, Xuemei Ding, Jianping Wang, Qiufeng Zeng, Yan Liu, Yue Xuan, Shanshan Li, Yadong Mu, Shiping Bai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-01-01
Serier:Frontiers in Nutrition
Fag:
adipose tissue
de novo lipogenesis
hepatic steatosis
iron homeostasis
lipid metabolism
mice
Online adgang:https://www.frontiersin.org/articles/10.3389/fnut.2025.1725052/full
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