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The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK

In previous work, we characterized the strong neuroprotective properties of the marine compound Psammaplysene A (PA) in in vitro and in vivo models of neurodegeneration. Based on its strong neuroprotective activity, the current work attempts to identify the physical target of PA to gain mechanistic...

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Principais autores: Marco Boccitto, Nayoung Lee, Satoshi Sakamoto, Lynn A. Spruce, Hiroshi Handa, Jon Clardy, Steven H. Seeholzer, Robert G. Kalb
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2017-08-01
סדרה:Marine Drugs
נושאים:
Psammaplysene A
neurodegeneration
foxo
HNRNPK
RNA metabolism
גישה מקוונת:https://www.mdpi.com/1660-3397/15/8/246
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