Increased IL4I1 expression predicts poor survival and modulates the immune microenvironment in acute myeloid leukemia

Abstract Background The immunometabolic enzyme Interleukin-4-induced-1 (IL4I1) is implicated in cancer pathogenesis, yet its specific function and clinical relevance in acute myeloid leukemia (AML) remain unclear. Methods Comparative analysis of IL4I1 mRNA levels between AML patients and normal cont...

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Hauptverfasser:	Jinlong Huang, Jinyuan Chen, Liangyong Yang, Zhiyong Zeng, Junfang Lin, Guilan Lai, Yanquan Liu, Xiaoqiang Zheng, Apeng Yang, Qingjiao Chen, Jinfeng Dong, Ping Chen, Junmin Chen, Liying Yu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	Acute myeloid leukemia IL4I1 Biomarker Poor prognosis Immune infiltration
Online-Zugang:	https://doi.org/10.1186/s12967-026-07814-x
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