Familial patterns of immune dysregulation in CVID: insights from B- and T-cell phenotyping and antibody profiling

IntroductionCommon Variable Immunodeficiency (CVID) is a heterogeneous immune disorder characterized by a broad range of clinical manifestations. Its etiology is not yet fully understood. To gain insights into the immunological background of CVID in patients without a clearly defined genetic cause,...

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Principais autores:	Suzanne E. T. Comans, Evelien G. G. Sprenkeler, Mischa H. Koenen, Elles Simonetti, Bram Van Cranenbroek, Esther Van Rijssen, Riet Strik-Albers, Hans J. P. M. Koenen, Jacques J. M. van Dongen, Lilly M. Verhagen, Marien I. de Jonge, Stefanie S. V. Henriet
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-03-01
Colecção:	Frontiers in Immunology
Assuntos:	antibodies common variable immunodeficiency (CVID) familial pattern immunophenotyping mucosal immunology primary immunodeficiency
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1741900/full
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