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Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling

Physical or psychological stress can cause an immunologic imbalance that disturbs the central nervous system followed by neuroinflammation. The association between inflammation and depression has been widely studied in recent years, though the molecular mechanism is still largely unknown. Thus, targ...

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Principais autores: Tahir Ali, Qiang Hao, Najeeb Ullah, Shafiq Ur Rahman, Fawad Ali Shah, Kaiwu He, Chengyou Zheng, Weifen Li, Iram Murtaza, Yang Li, Yuhua Jiang, Zhen Tan, Shupeng Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-06-01
Serier:Frontiers in Molecular Neuroscience
Fag:
melatonin
neuroinflammation
oxidative stress
depression
luzindole
Online adgang:https://www.frontiersin.org/article/10.3389/fnmol.2020.00096/full
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